Abstract:
Introduction: Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) syndrome is a rare pediatric disorder consisting of a sudden onset of obsessive–compulsive disorder (OCD) and/or tics after a group A Streptococcus (GAS) infection.
Objective: reduce the morbidity associated with a late diagnosis.
Clinical case: A 5-year-old boy was admitted to the clinic due to refusal to eat. He had scarlet fever 2 months before and then reccurent fever episodes. He was depressed, and had obvious eye-blinking tics, increased urinary frequency; behavior changeS, With child's uncle was diagnosed OCD. In the hospital treatment, a clinical history was identified with PANS-PANDAS diagnostic criteria. She exhibited a relapsing-remitting clinical course, as described in the literature, with poor response to first-line treatments.
Conclusion: Although there are over years of research of the PANDAS syndrome, there is still a stringent need to a better definition of clinical manifestations, precise biological markers and neuroimaging tests in order to establish a therapeutic protocol following correctly drawn.
Keywords: Pediatric Autoimmune Neuropsychiatric Disorders, group A Streptococcus (GAS) infection, obsessive–compulsive disorder (OCD)
Audience TakeWay
- Sharing information will help us manage children, which is important both for personal experience and for the clinic.
- Raising awareness to recognize the disease, since it is still an illness that often goes unnoticed by many health professionals.
