Procedural pain and discomfort during pediatric medical interventions remain a significant challenge for healthcare providers and families alike. While clinical guidelines emphasize pain management and child-centered care, little is known about how parents cognitively frame these [....] » Read More
Miscarriage and stillbirth are not rare events and losing a baby can have an overwhelming and long-term impact on parents, existing and subsequent children, and on wider family Potential parents’ feelings of devastation, intense grief, anxiety, guilt and self-blame and loss [....] » Read More
Miscarriage and stillbirth are not rare events and losing a baby can have an overwhelming and long-term impact on parents, existing and subsequent children, and on wider family Potential parents’ feelings of devastation, intense grief, anxiety, guilt and self-blame and loss [....] » Read More
Neonatal respiratory care has been characterized by tremendous technological advances over the past five decades. However, lost in the shuffle are some tried and true aspects of care that remain relevant but have fallen into disuse. This presentation will summarize the recent his [....] » Read More
Research in the area of nutritional epigenetics involves the study of atoms in food that impact gene behavior. Prenatal co-exposures to heavy metals are known to cause changes in DNA methylation patterns which impact gene behavior in offspring. A recent literature review was cond [....] » Read More
Objectives: Neonatal bacterial meningitis (NBM) is a severe invasive infection of the central nervous system and a leading cause of early-life mortality and long-term neurodevelopmental impairment. Although its case-fatality ratio has declined over time, the burden of mortality a [....] » Read More
Acute respiratory infections are the leading group of illnesses with the highest morbidity and mortality rates in children under 5 years of age. Respiratory infections are divided into two types: upper respiratory tract infections and lower respiratory tract infections. Upper res [....] » Read More
Neonatal sepsis remains a critical public health concern in low- and middle-income countries such as Nepal, where limited neonatal care resources and delayed diagnosis contribute to significant morbidity. Although survival rates have gradually increased with improvements in neona [....] » Read More
Child mental health is essential for emotional regulation, social interaction, learning capacity, and overall wellbeing. Childhood emotional and behavioral disorders are increasingly recognized as major public health concerns worldwide, affecting children’s academic perform [....] » Read More
Introduction: Autism spectrum disorder is a neurodevelopmental disorder that restricts participation in normal life activities. A critical challenge is the early identification and intervention of children with autism spectrum disorder, which is essential for enhancing the qualit [....] » Read More
Case report: A 14 month-old boy was referred from primary health care center to our outpatient clinic with history of empty right hemi-scrotum since birth. On examination, the right hemiscrotum was undeveloped and the right testis was impalpable. The left testis was normally [....] » Read More
Background: Rapid identification of pathogens in pediatric sepsis is critical for optimizing antimicrobial therapy and improving outcomes. This study aimed to evaluate the clinical impact of the multiplex PCR-based BioFire® Blood Culture Identification 2 (BCID2) Panel on the [....] » Read More
Background: Opsoclonus-myoclonus ataxia syndrome (OMAS) is a rare, immune-mediated neurological disorder of childhood, frequently associated with neuroblastoma. Its clinical presentation may overlap considerably with infectious or autoimmune encephalitis, particularly during the [....] » Read More
Antibiotics are administered to many preterm newborns and to a substantial proportion of term infants in the hours after birth due to risk for early-onset sepsis. The approaches taken to determine which newborns should be evaluated for early-onset sepsis, and what type and durati [....] » Read More
Newborn metabolic screening had its origin in the 1960s with the introduction of the Guthrie Bacterial Inhibition Assay (BIA) for PKU. For nearly 20 years, the BIA was used to screen for PKU plus a number of additional disorders including maple syrup urine disease, tyrosinemia, a [....] » Read More
Pediatric Chest Pain is a common clinical condition among the Pediatric population. Acute chest pain often results in presentation to urgent care or emergency services The recognition and treatment of emergent causes of pediatric chest pain is of utmost importance in improving cl [....] » Read More
Objective: To investigate the effect of and Acupuncture on brain plasticity and motor development in children with cerebral palsy. Investigate effect on mechanism of apoptosis of brain nerve cells, regulating the expression of neurotrophic factors, promoting the remodeling of ner [....] » Read More
The limbic system, crucial for emotions, memory, motivation, circadian rhythms, and behavior, is often affected in childhood developmental disabilities (CDD) like ADHD, autism (ASD), and mood disorders, showing altered structures (especially the amygdala and hippocampus) and conn [....] » Read More
Background: Early neurological assessment in infancy aims to identify infants at risk for Cerebral Palsy (CP) through the evaluation of tone, posture, and early motor patterns. Among these assessments, the Hammersmith Infant Neurological Examination (HINE) is widely used as a sta [....] » Read More
Objectives: To evaluate the feasibility and effectiveness of the Communication Observation Card (COC) for community-based identification of Autism Spectrum Disorder and other neurodevelopmental disorders in children younger than two years of age. Methods: A prospective communi [....] » Read More
Objective: To determine the frequency of predictors which are related to poor treatment outcomes in term newborns presenting with transient tachypnea during the first 24 hours of birth in the Emergency Department of Tertiary Care Hospital. Background: Maternal history of diabete [....] » Read More
Envisaging preventive strategies into pediatric care is key to better child health outcomes. In this context, it is pertinent to note that pediatric health care (a field of medical specialty focusing on the health of individuals from birth until the age 18 or 21 years) has e [....] » Read More
Despite the fact that breathing clean air is a basic human right, air pollution (defined as “contamination of the indoor or outdoor atmosphere by harmful substances”) has become a major global threat to human health and well-being. Poor air quality has impact o [....] » Read More
Neonatal and pediatric health outcomes in peri-urban informal settlements are shaped by complex, interrelated ecological factors. This study examines how economic hardship, early pregnancies, and survival-driven transactional sex influence child health outcomes in Epworth, Zimbab [....] » Read More
Background: Neonatal jaundice remains one of the most common conditions requiring postnatal monitoring and treatment. Home-based phototherapy has increasingly been implemented within community neonatal services in the National Health Service as part of expanding “Hospital a [....] » Read More
1. Background: Neonatal sepsis is a time-critical condition in which delays in antibiotic administration are associated with increased morbidity and mortality¹. Guidance from the National Institute for Health and Care Excellence and the British Association of Perinatal Medic [....] » Read More
The world health organization recommends the use of Pyrazinamide for first line antituberculosis drug for the treatment of TB. Developing age-appropriate dosage forms is critical for effective pharmaceutical therapy, particularly chronic conditions like paediatric Tuberculosis (T [....] » Read More
Background and aims: Perinatal asphyxia and neonatal encephalopathy remain leading causes for mortality and morbidity, urging markers of neurodevelopmental outcome in hypothermia-treated (HT) newborns. This study evaluated whether established clinical parameters and neuroimaging [....] » Read More
Background: Preterm neonates have a critically small circulating blood volume of 85–90 mL/kg. Early admission phlebotomy removes a significant proportion of this volume. Umbilical cord sampling (UCS) in place of admission phlebotomy is a practical blood-conservation strateg [....] » Read More
Background: Timely postnatal imaging and prophylactic antibiotics are essential in reducing renal injury and long-term morbidity of antenatally detected Urological abnormalities. This audit assessed compliance with three standards: i)Appropriate scan request timing; ii)Scan compl [....] » Read More
Trigger: Late Preterm Infants (LPIs) (34-36 weeks gestation) require specialized support due to unique developmental challenges that increase readmission risks. The initial assessment identified significant variability in existing discharge methodologies across a Southeaster [....] » Read More
Title : Physiological transition and resuscitation at birth
David J R Hutchon, Darlington Memorial Hospital, United Kingdom
Up to 10 percent of babies require assistance at birth to commence breathing. This has been traditionally carried out away from the mother after the umbilical cord has been clamped. Early cord clamping was a routine at most births until ten years ago and remains common in any bab [....] » Read More
Title : The biological value of proteins for pediatric growth and development: Advances and criticisms
Marlene Fabiola Escobedo Monge, University of Valladolid, Spain
In personalized nutrition, it is essential to account for the biological value of protein sources that underpin children’s growth and developmental needs. Although sufficient protein intake is fundamental for optimal physical and cognitive development, excessive intake may [....] » Read More
Title : The term rare or orphan disease: The diagnostic bias toward severe phenotypes
Ali Al Kaissi, Ilizarov Institute Traumatology and Orthopedics, Russian Federation
Organizations such as the European Medicines Agency and the U. S. Food and Drug Administration define orphan diseases mainly based on prevalence of diagnosed cases and the severity of the classic phenotype. Rare or Orphan disease, is a common term in practice, rare disease is onl [....] » Read More
Title : Bridging the gap between early detection of autism prodrome in infants, assessment and intervention
Hanna A Alonim, Bar Ilan University, Israel
The worldwide prevalence of autism points out of 2% of the population. Very early intervention may minimize the severity of the phenotypic presentation of autism during infancy when neural connections are being rapidly developed. However, intervention is contingent upon a diagnos [....] » Read More
Title : Personalized and Precision Medicine (PPM) as the unique healthcare model to secure the national health and wellness: From family planning and gestation period through human biosafety
Sergey Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
A new systems approach to diseased states and wellness result in a new branch in the healthcare services, namely, personalized & precision medicine (PPM). PPM as being the Grand Challenge to forecast, to predict and to prevent is rooted in a big and a new science generated by [....] » Read More
Title : Scoliosis care: Where anatomy and psychology intersect
Michael Ginzburg, University of California Davis Healthcare System, United States
Background: At the time of the intake, the patient was a 14-year-old Risser 1 female at the 91st percentile for height, presenting with a 39 degree thoracic curve spanning T5-T12 with an apex at T5 and 29 degree lumbar curve spanning T12 to L4 with an apex of L2, complicated by p [....] » Read More
Title : Summary of diagnostic experience for anomalous origin of the coronary arteries
Ning Ma, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, China
Objective: To summarize the diagnostic experience of echocardiography in pediatric patients with anomalous origin of the coronary arteries (AOCA), with a focus on identifying characteristic imaging features, analyzing the causes of missed diagnosis, and exploring strategies to im [....] » Read More
Title : Artificial intelligence assisted diagnosis and treatment of congenital heart disease
Xin Zhang, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, China
Congenital heart disease (CHD) is a prevalent condition affecting infants and children worldwide, and it is the most common type of birth defect in China. But the shortage of pediatric doctors and the uneven distribution of medical resources in China have led to the lack of an ef [....] » Read More
Title : Early predictors of orthotic effectiveness for full-time scoliosis TLSO cases
Michael Ginzburg, University of California Davis Healthcare System, United States
Scoliosis is a tri-planar condition of the spine that often requires multidisciplinary conservative outpatient treatment. The medical and allied health clinicians involved have their own workflows, schedules, concerns, and logistics with the patients and their families greatly be [....] » Read More
Title : Multidisciplinary QI collaboration in decreasing pediatric unplanned extubation
Yu Kawai, Mayo Clinic Children's, United States
Introduction: Unplanned Extubations (UE) are common, preventable adverse events in the neonatal and Pediatric intensive care units that can cause serious complications. Risk factors include inadequate sedation, poor ETT securement, clinician inexperience, and high staff workload. [....] » Read More
Title : Weight awareness among parents and health care providers in Sharjah, UAE
Naguib M Abdelreheim, University Hospital Sharjah, United Arab Emirates
Background: This study looks at weight perception among parents and health care providers in Sharjah, UAE. Methods: This study was done through reviewing 1000 patients files who visited the paediatric OPD in university hospital Sharjah (UHS) during 2015. The files were reviewed f [....] » Read More
Title : Meckel s diverticulitis causing distal ileal volvulus with ruptured mesenteric cyst in a child with severe bilateral pneumonia: A rare surgical emergency
Umashankar Palanisamy, Sudha Mother and Child Care Hospital, India
Ba?kgr?und: A?ute abd?men in ?hildren with severe pneum?nia p?ses a signifi?ant diagn?sti? ?hallenge. Abd?minal pain may initially be attributed t? l?wer l?be pneum?nia, delaying re??gniti?n ?f an underlying surgi?al path?l?gy. Me?kel's diverti?ulitis is an un??mm?n ?ause ?f [....] » Read More
Title : Bringing the promise of Personalized and Precision Medicine (PPM) to rare and orphan disorder care: How to use the latter to revolutionize pediatric services
Sergey Suchkov, N. D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
The greatest challenge of Personalized and Precision |Medicine (PPM) is to optimize pre-early (subclinical) diagnostics, predictive and prognostics procedures, and to identify curative therapies for every disease in a personalized way so that every individual gets benefit. To tha [....] » Read More
Title : Current challenges and future directions in neonatal care in developing countries
Muhammad Tahir Nadeem, DHA Hospital, Pakistan
Neonatal health continues to be a major public health priority worldwide, particularly in developing countries where healthcare resources are often limited. Despite significant advances in neonatal medicine, neonatal mortality and morbidity remain substantial challenges due to pr [....] » Read More
Title : Acute gastrointestinal injury in children on ECMO: An analysis of risk factors
Bin Yan, Gansu Provincial Maternity and Child-care Hospital, China
Objective: To investigate the risk factors associated with acute gastrointestinal injury (AGI) during extracorporeal membrane oxygenation (ECMO) therapy in pediatric patients. Methods: This retrospective study included 62 pediatric patients who were treated with E [....] » Read More
Title : Vaccine co-administration in babies in the Lombardy region (Italy): An effective way to improve coverage
Veronica Deysi Genoveva Colombo, ASST Bergamo Ovest, Italy
Background: In European after pandemic period for SARS Covid 2019-2023 we are encountered serious complications and mortality data associated with infectious diseases increase with age. Vaccination against influenza and Covid (annually) are recommended for children and specific r [....] » Read More
Title : Improving breastfeeding rates at discharge from Russells Hall Neonatal Unit: A quality improvement project at a district general hospital
Olivia Abrams, Russells Hall Hospital, United Kingdom
The benefits of breastfeeding to the newborn infant are long-established, and the administration of human milk is considered the gold standard for infant feeding universally. Human milk is specifically designed to pass on specific antibodies from mother to child, and new evidence [....] » Read More
Title : Perforated Meckel’s diverticulitis in an extremely preterm, very low birth weight infant
Umashankar Palanisamy, Sudha Mother and Child Care Hospital, India
Background: Meckel’s diverticulum is an uncommon cause of intestinal perforation in extremely preterm and very low birth weight (VLBW) infants and may clinically mimic spontaneous intestinal perforation or necrotizing enterocolitis. Case Presentation: A male infant was d [....] » Read More