Abstract:
Objective: To investigate the effect of and Acupuncture on brain plasticity and motor development in children with cerebral palsy. Investigate effect on mechanismof apoptosis of brain nerve cells, regulating the expression of neurotrophic factors, promoting the remodelingof nerve synaptic structure and motor development in young rats with cerebral palsy. To evaluate the effect and mechanism of acupuncture on cerebral palsy. The nerve repair effect of acupuncture on cerebral palsy.
Methods: In this study, 146 cases of brain injury and1078cases of cerebral palsy were included by randomized controlled study with ICF Gross motor function measure ,Peabody fine motor function, Gesell, muscle tension, joint activity, activityof daily living transcranial doppler, skull B ultrasound, Brain Nuclear Magnetic Resonance Imaging MRI,Positron Emission Tomography SPECT, Diffusion tensor tractography evaluationmethod.
Results: The recovery rate of extracellular space (92.3%) was significantly higher than that of thecontrol group (70.8%) (P <0.05), Transcranial Doppler,TCD total efficiency (79.3%) was significantly higher than that in the control group (51.8%) (P <0.05). Acupuncture to promotingthe development of neurological and cognitive movement under 6 months children, effectively reduce the neurological sequelae.The total effective rate of the children with cerebral palsy was 87% in the acupuncture group, which was significantly higher than that of the control group (P<0.01). The total effective rate of Brain MRI was 59.55% in the acupuncture group and 13.25% higher than that in the control group (P <0.01). The total effective rate was 91.3%in the 1year follow-up group, which was significantly higher than that in the control group (P <0.01). the FA value of white matter fiber bundle was significantly higher than that of acupuncture at 60 times (P <0.05). The recovery rate of ultrasonous brain injury (86.7%) in acupuncture group was significantly higher than that in control group (64.4%) (P <0.05). The recovery rate of brainSPECT in acupuncture group was 96.4%, which was significantly higher than that in the control group (P <0.01).
Conclusion: Acupuncture rehabilitation not only promote the development of white matter andgray matter in children with cerebral palsy, but also promote the brain function of children with cerebral palsy remodeling and compensation, and promote social adaptation, language andother cognitive function development, children with cerebral palsy movement and fine motor function development and recovery, improve the children's self-care ability.
Keywords: Cerebral palsy, Acupuncture, Nerve repair, remodeling, motor function
