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EPN 2018

Irina N Zakharova

Irina N Zakharova, Speaker at Neonatal conferences
Russian medical Academy of continuing professional education, Russian Federation
Title : Prevention of vitamin D deficiency in infants and children in the Russian federation: Modern approaches to correction


Objective: To develop recommendations and schemes of medicamental prevention and correction of vitamin D deficiency in children in Russia. Methods: During the Rodnichok study 1614 children under three years of age were examined from November 2013 till December 2016 in different regions of Russia. Vitamin D status was evaluated based on calcidiol level in serum. Results: Vitamin D deficiency in autumn-spring period is observed in more than half of Russian children of the first age of life (52.8%). The most vulnerable to vitamin D deficit group is breastfed infants. Formula feeding without cholecalciferol medications supplementation does not satisfy children’s need for vitamin D. Hypovitaminosis D should be prevented medicamentally in all children during the first year of life irrespectively of the type of feeding. Cholecalciferol medications supplementation raises level of vitamin D in children significantly and in most cases prevents deficit, but not necessarily leads to reaching 30 ng/ml. 25(??)D serum level correlates strongly with cholecalciferol medications dosage, at the same time intake of vitamin D medications during the first year of life in dosage 1000-1500 IU/day necessarily raises level of vitamin D without risk of overdose. Conclusion: The unidirectional nature and comparable efficacy in young children in all cities of the study (Arkhangelsk, Moscow, Kazan, Stavropol) were demonstrated, which allows to recommend the proposed scheme of hypovitaminosis D correction in Russia. Keywords: vitamin D, hypovitaminosis D, correction


Prof. Irina Zakharova graduated from D.I. Ulyanov Medical University in Kuibyshev, USSR, in 1979. After that she worked as a pediatrician in different regions in the USSR and other countries. In 1989 she completed her residency in pediatrics in the Russian Medical Academy of Continuous Professional Education, Moscow. She defended there a candidate thesis in 1994 and a doctoral thesis in 2000 (Clinic and diagnostics aspects of tubulointerstitial kidney diseases in children). In 2001-2008 she worked as a professor of department of pediatrics, since 2008 – as a head of this department. Prof. Irina Zakharova currently is also the Chairman of the Association of Doctors on Assistance in Training of Pediatricians of Russia, the Chairman of the Association of Doctors on Vitamin D Research, editor-in-chief of the Concillium Medicum Pediatrics and Medical Council Pediatrics.