Abstract:
Solid tumors discovered at birth or during the first month after delivery are rare. Neonatal tumors are often benign. Malignant tumors in neonates represent only 2% of all malignancies in childhood. Some tumors that appear histologically malignant may show benign behavior, whereas apparently benign tumors may be fatal by virtue of their site of origin, which makes neonatal tumors one of the most difficult diagnostic and therapeutic challenges in the neonatal units. Planning the diagnostic evaluation and therapeutic interventions necessitates a multidisciplinary approach that involves the neonatology, radiology, surgery, pathology, hematology, and oncology services. Here we provide a general overview of the most common tumors seen in the newborn period and address some of the initial approach to their treatment.