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Frederico Ribeiro Pires, Speaker at Pediatrics Conferences
Pediatric Intensive Care Unit, Children’s Hospital of Brasília, Brasília - Federal District, Brazil


Anemia and thrombocytopenia are common in the pediatrician’s clinical routine. But are we prepared for the differential diagnoses and the serious risks that we can take with the wrong conduct? Thrombotic microangiopathies encompass a set of pathologies that evolve with nonimmune hemolytic anemia and thrombocytopenia, but underdiagnosed in the pediatric age group. Will be reported the case of a child with a diagnosis of systemic lupus erythematosus (SLE), macrophagic activation syndrome (MAS) and thrombotic thrombocitopenic purpura (TTP), which evolved to death. Due to the severity of thrombotic microangiopathies and their underdiagnosis, I propose a flowchart of ducts in the anemic and thrombocytopenic patients, with great care in platelet transfusion, to avoid the tragic outcome.


Dr Frederico Ribeiro Pires is a pediatric intensivist with a specialist degree from the Brazilian Society of Intensive Care Medicine. Assistant physician of the pediatric ICU of the Children’s Hospital of Brasília and professor of pediatrics at the University of Brasília. In addition to his work, he reviews articles for some medical journals and has articles published in the area of thrombotic meningitis and microangiopathy. Currently, he does research with vancomycin and meropenem in pediatric intensive care.