EPN 2022

Sophie Noelle Hackenbruch

Sophie Noelle Hackenbruch, Speaker at Pediatrics Conferences
Mater Dei Hospital, Malta
Title : Maternal and Gestational Risk Factors of Congenital Diaphragmatic Hernia

Abstract:

Background and Aim: Congenital diaphragmatic herniae (CDH) have a high incidence rate on the Maltese islands, but little is known about their associations and maternal risk factors. A nationwide study in a country where abortion is still illegal, allowing more data to be used, has been conducted to shed light on some possible risk factors of the development of a congenital diaphragmatic hernia.

Materials and Methods: The study is a population based retrospective analysis including CDH cases from 1993 until 2016, which was gathered from the Directorate of Health information and Research Malta Chi- squared analysis and risk ratio was used to examine associations between cases and controls.

Results: 55 cases were reported between 1993-2016. The cases make up 0.0644 percent of the total births during that period. Advanced maternal age was more likely in CDH cases (p=0.01). 18.2 percent of CHD cases were born at 1500-2499 grams compared to only 6.2 percent of controls with a significance of <0.001. No significance was found relating to infant gender (54.5% vs 50.9% p=0.404) and none in relation to plural births (3.6% vs 1.3% p=0.333).

Conclusions: Congenital diaphragmatic hernia was found to be associated with advanced maternal age and low birthweights. It was also confirmed having a congenital diaphragmatic hernia increases your chances of having further congenital anomalies.

What will audience learn from your presentation?

  • Diaphragmatic hernias are still a common anomaly faced in NPICU. This study highlights the risk factors associated with diaphragmatic hernias allowing clinicians to preempt and be more cautious about a possible anomaly.
  • It is the only national research of its type in a country where abortion is illegal meaning no cases are lost, giving more reliable results.
  • More research needs to be carried out in causation and risk factors of diaphragmatic hernias, a study like this could open the doors to that.

Biography:

Dr. Sophie Noelle Hackenbruch studied Doctor of Medicine and Surgery at the University of Malta and graduated in 2020. She continued working at Mater Dei Hospital, Malta since 2020 as a foundation doctor. She has participated in many research projects and audits since starting her job. She is currently undertaking a level 7 diploma in strategic management.

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