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Juvenile Rheumatoid Arthritis

Juvenile Rheumatoid Arthritis (JRA), also known as Juvenile Idiopathic Arthritis (JIA), is a chronic autoimmune inflammatory disorder that primarily affects children under the age of 16, leading to persistent joint pain, swelling, and stiffness. This debilitating condition encompasses a heterogeneous group of arthritic diseases, with symptoms ranging from mild joint discomfort to severe systemic involvement. The etiology of JRA remains elusive, with genetic predisposition and environmental factors believed to contribute to its onset. The hallmark feature is inflammation of the synovium, the membrane lining the joints, which can eventually lead to joint damage and deformities. JRA is classified into several subtypes based on clinical manifestations, including oligoarthritis, polyarthritis, systemic arthritis, enthesitis-related arthritis, and psoriatic arthritis, each presenting distinct challenges in diagnosis and management. The unpredictable nature of JRA poses significant physical and emotional challenges for affected children and their families, often impacting their daily activities, school attendance, and overall quality of life. Early diagnosis and intervention are crucial to prevent long-term joint damage, and treatment approaches typically involve a combination of nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), biologics, and physical therapy. The multidisciplinary care of JRA patients involves rheumatologists, Paediatricians, physical therapists, and other healthcare professionals working collaboratively to tailor treatment plans to individual needs. Despite significant advances in understanding and managing JRA, ongoing research efforts strive to unravel its complexities, improve therapeutic options, and ultimately enhance the prognosis and well-being of children grappling with this challenging autoimmune condition.

Committee Members
Speaker at Pediatrics and Neonatology 2025 - Steven M Donn

Steven M Donn

University of Michigan Health, United States
Speaker at Pediatrics and Neonatology 2025 - Renee J Dufault

Renee J Dufault

Food Ingredient and Health Research Institute, United States
Speaker at Pediatrics and Neonatology 2025 - Catherine Fallet Bianco

Catherine Fallet Bianco

Sainte-Justine University Hospital, Canada
Speaker at Pediatrics and Neonatology 2025 - Heather Hanna

Heather Hanna

Imperial College, United Kingdom
EPN 2025 Speakers
Speaker at Pediatrics and Neonatology 2025 - Ann L Smith

Ann L Smith

Novant Health Forsyth Medical Center, United States
Speaker at Pediatrics and Neonatology 2025 - Michael Ginzburg

Michael Ginzburg

UC Davis Health, United States
Speaker at Pediatrics and Neonatology 2025 - Adonna Francis

Adonna Francis

Imperial College, United Kingdom
Speaker at Pediatrics and Neonatology 2025 - Jo Vrancken

Jo Vrancken

PXL University College, Belgium
Speaker at Pediatrics and Neonatology 2025 - Bilal Tahir

Bilal Tahir

James Paget University Hospital, United Kingdom
Speaker at Pediatrics and Neonatology 2025 - Reshma Vithayathil

Reshma Vithayathil

Bedford Hospital, United Kingdom
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