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Paediatric Endocarditis

Paediatric endocarditis is a rare but serious medical condition that involves inflammation of the inner lining of the heart chambers and heart valves in children. Typically caused by bacterial infection, it poses a significant threat to the Paediatric population, particularly those with congenital heart defects or pre-existing heart conditions. The pathogenesis of Paediatric endocarditis begins when bacteria enter the bloodstream, often through dental procedures, surgeries, or infections in other parts of the body. These bacteria then adhere to the damaged areas of the heart, forming vegetations that can impair valve function and lead to systemic complications. The clinical presentation varies widely, encompassing symptoms such as fever, fatigue, weight loss, and a characteristic heart murmur upon physical examination. Timely diagnosis is challenging, as the symptoms can be subtle and nonspecific, making it imperative for healthcare providers to maintain a high index of suspicion, especially in children with known risk factors. Diagnostic modalities include blood cultures, echocardiography, and other imaging studies to assess the extent of valve damage and potential complications. Treatment often involves a prolonged course of intravenous antibiotics, selected based on the identified causative microorganism, and may require hospitalization. Surgical intervention may be necessary in severe cases with significant valve destruction or complications, aiming to repair or replace affected valves. Prognosis hinges on prompt diagnosis and intervention, and the risk of morbidity and mortality underscores the importance of preventive measures, such as antibiotic prophylaxis in high-risk individuals undergoing certain medical procedures. Collaborative efforts between Paediatricians, cardiologists, and infectious disease specialists are crucial to ensure comprehensive and effective management of Paediatric endocarditis, minimizing long-term cardiac sequelae and optimizing the overall health outcomes for affected children.

Committee Members
Speaker at Pediatrics and Neonatology 2025 - Steven M Donn

Steven M Donn

University of Michigan, United States
Speaker at Pediatrics and Neonatology 2025 - Renee J Dufault

Renee J Dufault

Food Ingredient and Health Research Institute, United States
Speaker at Pediatrics and Neonatology 2025 - Catherine Fallet Bianco

Catherine Fallet Bianco

Sainte-Justine University Hospital, Canada
Speaker at Pediatrics and Neonatology 2025 - Hanna Alonim

Hanna Alonim

The Mifne Center for Treatment Research and Training, Israel
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