HYBRID EVENT: You can participate in person at London or Virtually from your home or work.
Prader-Willi Syndrome

Prader-Willi Syndrome (PWS) is a complex and rare genetic disorder that manifests with a constellation of physical, cognitive, and behavioral challenges. Named after the Swiss doctors who first described it in 1956, Prader-Willi Syndrome is primarily caused by a deletion or absence of certain genes on chromosome 15, and less frequently by maternal uniparental disomy or imprinting defects. One of the hallmark features of PWS is insatiable hunger, leading to severe overeating and obesity if not rigorously controlled. This hyperphagia, coupled with a reduced metabolic rate, presents a considerable risk for obesity-related complications. Individuals with PWS often exhibit distinctive facial features, such as almond-shaped eyes, a narrow forehead, and a downturned mouth. Beyond the physical characteristics, the syndrome is associated with intellectual disabilities, learning difficulties, and varying degrees of developmental delays. Behavioral issues are common, encompassing obsessive-compulsive tendencies, skin-picking, and temper outbursts. Hypotonia, or low muscle tone, is prevalent in infancy, affecting motor skills and milestones. As individuals with PWS age, they may also experience hormonal imbalances, including growth hormone deficiency, leading to short stature. Additionally, sleep disturbances, psychiatric disorders, and social challenges contribute to the complex clinical picture of Prader-Willi Syndrome. A multidisciplinary approach involving medical, nutritional, and behavioral interventions is crucial for managing PWS, and ongoing research seeks to enhance our understanding of this intricate disorder to improve the quality of life for those affected and support their families and caregivers.

Committee Members
Speaker at Pediatrics and Neonatology 2025 - Steven M Donn

Steven M Donn

University of Michigan, United States
Speaker at Pediatrics and Neonatology 2025 - Peter Averkiou

Peter Averkiou

Florida Atlantic University, United States
Speaker at Pediatrics and Neonatology 2025 - Catherine Fallet Bianco

Catherine Fallet Bianco

Sainte-Justine University Hospital, Canada
Speaker at Pediatrics and Neonatology 2025 - Jeanne Magagna

Jeanne Magagna

Great Ormond Street Hospital for Children, United Kingdom
EPN 2025 Speakers
Speaker at Pediatrics and Neonatology 2025 - Ann L Smith

Ann L Smith

Novant Health Forsyth Medical Center, United States
Speaker at Pediatrics and Neonatology 2025 - Tehreem Fatima

Tehreem Fatima

University of Connecticut, United States
Speaker at Pediatrics and Neonatology 2025 - Rohit Kumar

Rohit Kumar

James Cook Hospital, United Kingdom
Speaker at Pediatrics and Neonatology 2025 - Nicola Webster

Nicola Webster

North West Regional Hospital, Australia
Speaker at Pediatrics and Neonatology 2025 - Tadel Karolina

Tadel Karolina

Wroclaw Medical University, Poland
Speaker at Pediatrics and Neonatology 2025 - Vlad Dima

Vlad Dima

Filantropia Clinical Hospital, Romania

Submit your abstract Today

Watsapp